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North Queensland Toyota Cowboys Head Coach Todd Payten has made a late change to his starting side for tonight's clash against the South Sydney Rabbitohs at Optus Stadium. 

Sam McIntyre will start in the second row, with Jeremiah Nanai shifting back to the bench. 

Zac Laybutt is the final player to drop out of the 22-man squad named on Tuesday. 

Saturday’s game kicks off at 3.30pm (5.30pm AEST).

>>> Payten: His form over the last couple of weeks has been outstanding

Cowboys team to play Rabbitohs:

1. Scott Drinkwater

2. Rob Derby

3. Jaxon Purdue

4. Viliami Vailea

5. Murray Taulagi

6. Tom Dearden (c)

7. Jake Clifford

8. Jordan McLean

9. Reece Robson

10. Jason Taumalolo

12. Kai O’Donnell

14. Sam McIntyre

13. Reuben Cotter (c)

Interchange

15. Jeremiah Nanai

16. Griffin Neame

17. Coen Hess

18. Harrison Edwards

18th man

22. Tom Mikaele