Penrith Panthers forwards Scott Sorensen and Moses Leota have been ruled out of Saturday's clash with the North Queensland Toyota Cowboys at Queensland Country Bank Stadium.
Lindsay Smith and Luke Garner come into the starting side, with Matt Eisenhuth and Mavrik Geyer coming onto the bench.
Panthers team list
1. Dylan Edwards
2. Sunia Turuva
3. Izack Tago
4. Taylan May
5. Brian To'o
6. Jarome Luai
7. Nathan Cleary
15. Lindsay Smith
9. Mitch Kenny
10. James Fisher-Harris
17. Luke Garner
12. Liam Martin
13. Isaah Yeo
Interchange
14. Daine Laurie
16. Liam Henry
18. Matt Eisenhuth
21. Mavrik Geyer
Reserves
19. Paul Alamoti
20. Brad Schneider