North Queensland Toyota Cowboys second-rower Tom Gilbert (family matter) will miss Friday's clash with the Warriors at Queensland Country Bank Stadium.
Luciano Leilua will take his place in the starting side, with Jamayne Taunoa-Brown coming onto the bench.
Ben Hampton and Connelly Lemuelu are the two other players to drop out of the 22-man squad named on Tuesday.
Cowboys team to play Warriors:
2. Kyle Feldt
4. Peta Hiku
6. Tom Dearden
7. Chad Townsend (c)
9. Reece Robson
10. Reuben Cotter
15. Luciano Leilua
12. Jeremiah Nanai
13. Jason Taumalolo (c)
Interchange
16. Coen Hess
17. Griffin Neame
Reserves
20. Jake Granville
21. Brendan Elliot